Rybelsus (semaglutide)

Rybelsus (semaglutide) is an oral medication prescribed for adults with type 2 diabetes mellitus to control blood sugar levels. While it has shown potential in aiding weight loss, it is not FDA-approved for this purpose. Rybelsus works by increasing insulin release and decreasing glucagon secretion, potentially slowing gastric emptying after eating. It belongs to the GLP-1 receptor agonists class of medicines and contains the same active ingredient as Wegovy and Ozempic injections.

Rybelsus is contraindicated for those with multiple endocrine neoplasia type 2, a history of medullary thyroid cancer, insulin-dependent diabetes, or diabetic ketoacidosis. It's also unsuitable for those allergic to semaglutide or with certain medical conditions such as stomach or intestinal disorders, gallbladder disease, pancreatitis, diabetic retinopathy, or kidney disease. The medication is not approved for individuals under 18 years old.

Dosage typically starts at 3 mg once a day for 30 days, then may increase to 7 mg daily. If additional glycemic control is needed, the dose can be increased to a maximum of 14 mg daily. Rybelsus should be taken once daily, swallowed whole with a small amount of water, and at least 30 minutes before eating or drinking anything else. Overdosing on Rybelsus can lead to severe nausea, vomiting, or low blood sugar. Side effects may include allergic reactions, vision changes, mood alterations, symptoms of thyroid tumors, pancreatitis, gallbladder problems, low blood sugar, kidney problems, stomach flu symptoms, upset stomach, heartburn, and dizziness.

Rybelsus can slow digestion, potentially affecting the absorption of other oral medicines. Patients should inform their doctors about all medications they are taking, including over-the-counter drugs, vitamins, and herbal products​​​​​​​​.

Regarding coupons for Rybelsus, eligible commercially insured patients may be able to significantly reduce their prescription costs. With the Rybelsus Savings Card, they might pay as little as $10 for their prescription. This offer is valid for up to 12 uses, with a maximum monthly savings of $250​​.

Furthermore, eligible patients can pay as little as $10 for a 1-, 2-, or 3-month prescription of Rybelsus. For a 7 mg or 14 mg dose, this offer applies to 1-, 2-, or 3-month supplies, while for a 3 mg dose, the cost can be as low as $10 each month. This offer is only applicable to eligible, commercially insured patients with product coverage. The maximum savings possible are $300 per 1-month supply, $600 per 2-month supply, or $900 per 3-month supply. There are eligibility and other restrictions, which interested individuals can review on the Rybelsus website​​​​.